Bruce Randall Donald -- Publications
Professor of Computer Science, Biochemistry, and Chemistry
Duke University

Predicting Cancer Resistance Mutations by Pareto Optimization Over Multistate Protein Design

Predicting Resistance Mutations using Protein Design Algorithms.
PNAS (2010).

Computational Structure-Based Redesign of Enzyme Activity.
PNAS (2009).

Protein Design by Provable Algorithms
(in Comm. ACM, 2019).

Computational design of a tight binder to KRas,
an “undruggable” cancer target

PLoS Computational Biology

  Cover Article, Chemistry & Biology 2007. [Caption]

  Redesigning the PheA Domain of Gramicidin Synthetase.
Biochemistry 2006; 45 (51):15495-15504.

  Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis. (J. Biol. Chem. 2003).

  Cover article, J. Eukaryotic Microbiology (2003).
  Cover article, PROTEINS (2012).

Complete ensemble of NMR structures of the unphosphorylated human cardiac phospholamban pentamer. PDB ID: 2HYN (Proteins, 2006)

List of Selected Papers, Broken into categories